Biotech

Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing question: Could a single molecule switch between two different roles like a seesaw? This idea […]

Ribonucleotide reductases (RNR) are indispensable enzymes that convert ribonucleotides to deoxyribonucleotides (dNTPs), the precursors to make up DNA. Because DNA synthesis is fundamental to cell survival, RNR activity must be tightly controlled. In bacteria, this […]

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 possible variants—more combinations than atoms in the observable universe. Traditional engineering methods might test hundreds of […]

Scientists have long sought to understand why some plants are fragrant powerhouses while others remain subtle. Now, a research team from the Hebrew University of Jerusalem has cracked a genetic “bottleneck,” using precision gene editing […]

DNA is the blueprint of life. Genes encode proteins and serve as the body’s basic components. However, building a functioning organism also requires precise instructions about when, where, and how much those components should be […]

University of Missouri researchers have released the world’s largest collection of protein models with quality assessment—a groundbreaking new resource that could accelerate drug development for diseases such as Alzheimer’s and cancer. The database, called PSBench, […]

A novel method to manipulate the inner structure of cells connects several scientific fields and could represent a significant step in the treatment of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease. Dr. Travis Craddock, […]

A Purdue University digital forestry team has created a computational tool to obtain and analyze urban tree inventories on public and private lands with record-breaking speed at an unprecedented scale. The team accomplished the feat […]

How does our DNA store the massive amount of information needed to build a human being? And what happens when it’s stored incorrectly? Jesse Dixon, MD, Ph.D., has spent years studying the way this genome […]

Bioengineered E. coli bacteria can now produce a group of compounds with anticancer, anti-HIV, antidiabetic and anti-inflammatory activities. The Kobe University achievement is the result of a rational design strategy that yields a platform for […]