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AI-designed proteins built from scratch can recognize specific compounds

April 9, 2026 Phys.org

Professor Gyu Rie Lee of the Department of Biological Sciences successfully designed artificial proteins that selectively recognize specific compounds using AI through joint research with Professor David Baker. The research, published in the journal Nature […]

Biotech

Unlocking the hidden metabolism of algae to advance the promise of renewable fuels and sustainable biomass

April 9, 2026 Phys.org

Researchers at the Donald Danforth Plant Science Center have solved a long-standing mystery of how a model green microalga reorganizes its central metabolism to supercharge growth when given access to both light and a carbon […]

Biotech

AI diffusion models tailor drug molecules to custom-fit protein targets, speeding drug development and evaluation

April 9, 2026 Phys.org

University of Virginia School of Medicine scientists have developed a bold new approach to drug development and discovery that could dramatically accelerate the creation of new medicines. UVA’s Nikolay V. Dokholyan, Ph.D., and colleagues have […]

Biotech

Decoy molecules trick soil bacteria into attacking persistent pollutants without genetic engineering

April 9, 2026 Phys.org

In a study published in the Journal of Materials Chemistry A, Nagoya University researchers demonstrated that native soil bacteria, when treated with decoy molecules, can degrade non-native compounds, including persistent pollutants such as dioxins, without […]

Biotech

Examining embryo model ethics beyond box-checking

April 9, 2026 Phys.org

In science, ethical guidelines ensure that research takes place in a way that respects public trust and is conducted responsibly. Traditional ethics approval procedures work well for projects following established practices, but they offer little […]

Biotech

A ‘stemness checkpoint’ helps control stem cell identity

April 8, 2026 Phys.org

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages. For nearly two […]

Biotech

Molecular ‘leash’ measures force-sensing protein activation at about 15 piconewtons

April 7, 2026 Phys.org

Researchers at the National University of Singapore (NUS) have built a molecular “leash” to pull directly on a force-sensing protein called Piezo1, and discovered it switches on at about 15 piconewtons, proving that it can […]

Biotech

How stem cell descendants preserve flexibility while maintaining distinct identities

April 7, 2026 Phys.org

Stem cells are the body’s ultimate shape-shifters, sustaining tissues by balancing two competing demands: maintaining their own population and generating specialized descendants. In many tissues, some early descendants can revert to a stem cell state […]

Biotech

What this AI epitope library means for vaccines, immunotherapy and biosensors

April 7, 2026 Phys.org

A new tool makes it possible to screen millions of tiny protein fragments and select those that can be recognized by the immune system. The CIC biomaGUNE Center for Cooperative Research in Biomaterials has developed […]

Biotech

3D microscopy reveals how a tick-borne virus reshapes human cells to replicate

April 7, 2026 Phys.org

Researchers at Umeå University show how tick-borne viruses remodel human cells into virus factories, using an advanced microscopy method. The findings provide new insight into how the virus replicates and matures, knowledge that may become […]

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